Yoo Min-woo's (Song Seung Heon) first love was Soh Eun-hye (Shin Ae). No love was greater than the love between these two...until Eun-hye get's into a car accident. Eun-hye dies...leaving one thing left behind...her heart. Shim Hye-won (Son Yeh Jin) has suffered from a terrible heart disease ever since childhood. Miraculously she finds that she will be obtaining a heart from a donor, Soh Eun-hye.

Suffering from the pain of a heartache, Min-woo goes to Paris to study...the memories of Eun-hye still rest in his heart. When he returns to Korea, fate takes a turn and brings Hye-won and Min-woo together. When the two first meet, Hye-won's heart (Eun-hye's heart), oddly beats faster when she is around Min-woo.

Park Jung-jae (Ryu Jin) is Hye-won's boyfriend. Park Jung-ah (Han Ji Hye) is Jung-jae's sister and she meets Min-woo in Italy and falls for him...

Hye-won doesn't know why or what she feels when she's with Min-woo...and Min-woo feels guilt toward Eun-hye, because the feeling of love rises once again as he continues to see Hye-won...